(Hypromellose Acetate Succinate)
Shin-Etsu AQOAT® (hypromellose acetate succinate) is our second enteric coating material, and it was developed for aqueous coating. Shin-Etsu AQOAT® was approved as a pharmaceutical excipient in Japan in 1987, and then in the United States and several European countries in 2001. In an aqueous system, a suspension containing Shin-Etsu AQOAT® (fine powder), triethyl citrate as a plasticizer, talc as an anti-tacking agent, and sodium lauryl sulfate as a wetting agent is typically used.
Shin-Etsu AQOAT® also shows excellent performance when it is used as a carrier for solid dispersions in order to enhance solubility of poorly soluble drugs.
Company:Shin-Etsu Chemical Co., Ltd.
Department:Cellulose & Pharmaceutical Excipients Department Organic Chemicals Division