Shin-Etsu AQOAT

(Hypromellose Acetate Succinate)

Shin-Etsu AQOAT® (hypromellose acetate succinate) is our second enteric coating material, and it was developed for aqueous coating. Shin-Etsu AQOAT® was approved as a pharmaceutical excipient in Japan in 1987, and then in the United States and several European countries in 2001. In an aqueous system, a suspension containing Shin-Etsu AQOAT® (fine powder), triethyl citrate as a plasticizer, talc as an anti-tacking agent, and sodium lauryl sulfate as a wetting agent is typically used.
Shin-Etsu AQOAT® also shows excellent performance when it is used as a carrier for solid dispersions in order to enhance solubility of poorly soluble drugs.

Series Name

  • AQOAT series

Applications

  • Enteric film coating for solid dosage forms such as tablets and granules
  • Drug solubility enhancement (solid dispersion)
  • Taste masking
  • Sustained release pH dependent
For Inquiries About This Product
  • Company:
    Shin-Etsu Chemical Co., Ltd.
  • Department:
    Cellulose & Pharmaceutical Excipients Department Organic Chemicals Division
  • Phone:
    +81-3-3246-5261